Observations on the clinical pharmacology and plasma concentrations of diacetolol, the major human metabolite of acebutolol.
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چکیده
منابع مشابه
Excretion of Acebutolol and its Major Metabolite Diacetolol into Infant Blood Circulation and the Breast Milk
Acebutolol (AC) is a chiral b-adrenergic blocking drug, which is useful clinically as the racemate in treating hypertension and is metabolized to an equipotent chiral metabolite, diacetolol (DC). In this paper we report a case of a 32 year old woman who was receiving AC during her pregnancy and lactating time for management of hypertension. The maternal plasma level and breast milk as well as c...
متن کاملExcretion of Acebutolol and its Major Metabolite Diacetolol into Infant Blood Circulation and the Breast Milk
Acebutolol (AC) is a chiral b-adrenergic blocking drug, which is useful clinically as the racemate in treating hypertension and is metabolized to an equipotent chiral metabolite, diacetolol (DC). In this paper we report a case of a 32 year old woman who was receiving AC during her pregnancy and lactating time for management of hypertension. The maternal plasma level and breast milk as well as c...
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ژورنال
عنوان ژورنال: British Journal of Clinical Pharmacology
سال: 1981
ISSN: 0306-5251
DOI: 10.1111/j.1365-2125.1981.tb01265.x